Macular degeneration is a degenerative disease in the elderly, which is directly related to age. The older the age, the more serious the degeneration of retinal tissue and macular function, the higher the probability of macular degeneration. In addition to age, high myopia is also an important cause of macular degeneration.
High myopia can affect the blood supply of retina and macula, and long-term ischemia will stimulate the generation and development of choroidal neovascularization, resulting in irreversible macular degeneration.
Macular degeneration is the age-related change in macular structure. The main pathological change is the decrease of retinal pigment epithelium cells * the role of outer membrane in the process of phagocytosis of the optic cells, resulting in the retention and excretion of the residual bodies in the cell basement of the disk membrane. Macular degeneration is mainly related to macular chronic light damage, choroidal vascular sclerosis and other factors, high myopia can also lead to macular degeneration, the specific situation is as follows.
If the degree of myopia exceeds 600 degrees, it belongs to high myopia. Some patients with high myopia axial length can be more than 26 mm, will lead to a series of pathological changes in the eye, this myopia is known as pathological myopia. The pathological changes caused by high myopia can lead to ischemia, hypoxia and retinal deformation near the macula, which is called macular degeneration.
Therefore, high myopia can lead to macular degeneration. Due to the extension of axial length, different layers of the eye wall are affected by different degrees of tension, resulting in blood circulation disorders, tissue ischemia, and eventually may develop into retinal degeneration and vitreous membrane cracks. Degeneration of the macular region also leads to the growth of CNV, a choroidal derived neovascularization. With the growth of CNV, there will be irreversible pathological changes in macular structure.
Macular degeneration will occur in 5-10% of patients with pathological myopia, and often both eyes will appear. The visual field of patients will be distorted and the central visual field will be damaged. The vision will gradually decline and the central vision will be completely lost. Pathological myopia is the main cause of macular degeneration in people under 50 years old. The specific disease is not clear, there are certain regional differences. The incidence of pathological myopia in Eastern countries is higher than that in western countries, which may be related to race.
Therefore, high myopia can lead to macular degeneration. The axial length of high myopia patients is too long, which causes compression to the eye wall. Long term compression can lead to circulatory disorders and choroidal derived vascular growth, leading to irreversible macular degeneration. Therefore, in order to prevent macular degeneration, it is recommended to strengthen eye care for people with high myopia. It is better to go to the eye hospital regularly for ophthalmic examination, early detection and early treatment.