Abstract: in order to make contact lenses safer to wear, researchers from the United States and Singapore have developed a new coating. After treating the contact lens surface with this new coating, the coating can withstand high temperature sterilization and maintain the integrity of chemical structure., Contact lenses have brought convenience to countless people, but in the process of wearing contact lenses, microorganisms are easy to breed on the lens surface, which increases the risk of keratitis and seriously threatens the wearer’s health. At the same time, the protein in tears is also easy to deposit on the surface of contact lenses, which will not only reduce the light transmittance of lenses, but also increase the wearer’s risk of eye infection. Cleaning and disinfection of lenses can improve the cleanliness of lens surface, but it can not completely avoid eye infection caused by microbial breeding., In the UK, 3 million people use contact lenses every year, and about 6000 cases of bacterial keratitis caused by bacterial infection occur almost every year, of which serious cases may lead to vision loss. Among them, the use of contact lenses has been identified as a specific risk factor for infectious keratitis. A new study presented at the Liverpool Annual Conference on General Microbiology in April showed that contact lenses can still cause eye bacterial infection even with disinfectant., To make contact lenses safer to wear, researchers from the United States and Singapore have developed a new coating. They use a high molecular material highly branched polyethyleneimine as the starting material, and connect three different chemical structures of polyethylene glycol, urea and catechol to its molecules through chemical reaction. Catechol structure enables this polymer coating to be very firmly connected to the surface of contact lenses to form a coating, while polyethylene glycol and urea can make it difficult for microorganisms and proteins in tears to adhere to the surface of the coating, making contact lenses easier to keep clean., The test shows that after the contact lens surface is treated with this new coating, the coating can withstand high temperature sterilization and maintain the integrity of chemical structure. During subsequent use, the coating can be maintained on the lens surface for up to seven days, effectively reducing the adhesion of microorganisms and proteins on the lens surface. At the same time, no significant toxicity was found in vitro. Because this coating can be easily combined with the existing contact lens production process, people in the industry have highly evaluated this research result.,
contact lenses bring convenience to countless people, but microorganisms are easy to breed on the lens surface during the wearing of contact lenses, which increases the risk of keratitis and seriously threatens the wearer’s health. At the same time, the protein in tears is also easy to deposit on the surface of contact lenses, which will not only reduce the light transmittance of lenses, but also increase the wearer’s risk of eye infection. Although cleaning and disinfection of lenses can improve the cleanliness of lens surface, it can not completely avoid eye infection caused by microbial breeding.
in the UK, 3 million people use contact lenses every year, and about 6000 cases of bacterial keratitis caused by bacterial infection occur almost every year, of which serious cases may lead to vision loss. Among them, the use of contact lenses has been identified as a specific risk factor for infectious keratitis. At the Liverpool General Microbiology annual conference held in April, a new research table presented by researchers showed that contact lenses can still cause eye bacterial infection even with disinfectant.
in order to make contact lenses safer to wear, researchers from the United States and Singapore have developed a new coating. They use a high molecular material highly branched polyethyleneimine as the starting material, and connect three different chemical structures of polyethylene glycol, urea and catechol to its molecules through chemical reaction. Catechol structure makes this polymer coating very firmly connected to the surface of contact lenses to form a layer of coating, while polyethylene glycol and urea can make it difficult for microorganisms and proteins in tears to adhere to the surface of the coating, making contact lenses easier to keep clean.
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tests show that after the contact lens surface is treated with this new coating, the coating can withstand high temperature sterilization and maintain the integrity of chemical structure. During subsequent use, the coating can be maintained on the lens surface for up to seven days, effectively reducing the adhesion of microorganisms and proteins on the lens surface. At the same time, no significant toxicity was found in vitro. Because this coating can be easily combined with the existing contact lens production process, people in the industry give a high evaluation of this research result.
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