Traditional Chinese medicine has advantages in the treatment of macular lesions

Abstract: Traditional Chinese medicine has certain advantages in the treatment of AMD. Since ancient times, traditional Chinese medicine has been treating this kind of disease according to syndrome differentiation. However, the deficiency is that it only takes improving visual acuity as the curative effect standard and lacks precise instruments to observe choroidal CNV lesions. Therefore, it lacks sufficient understanding of the occurrence and development of AMD.

macular disease is an ophthalmic disease of the elderly. If the condition is serious, it even leads to blindness. For this serious case, we must make every effort to actively treat it. How to choose the treatment method? How to choose medication? These are of great concern to patients. Let’s see the specific introduction below.

advantages of traditional Chinese medicine in the treatment of age-related macular degeneration

age-related macular degeneration is an ophthalmic refractory fundus disease, which is the primary cause of low vision and blindness in people over 50 years old. In China, the incidence rate of age-related macular degeneration is increasing year by year with the aging population. According to statistics, the incidence rate of people over 75 years old in China has reached 15.15%. At present, more than 1.75 million people in the United States suffer from the disease, which is expected to reach 3 million in 10 years.

in recent years, photodynamic therapy has brought some hope to the treatment of this disease, and then ushered in a new era of anti angiogenesis therapy. These two therapies are the mainstream methods of Western medicine to treat this disease. However, these two therapies still have many deficiencies. The former is expensive and easy to repeat, and it is difficult to determine whether vision can be improved. For many patients with low vision, such an expensive cost is unbearable. At present, anti vascular endothelial growth factor (anti VEGF) drugs, including ranibizumab (Lucentis), bevacizumab (Avastin) and pegaptanib (Macugen), have been used to treat neovascular AMD, namely wet AMD. Although these drugs are effective for CNV, it is difficult to control the recurrence of CNV, and there is a risk of local complications when repeated intravitreal administration is required; In particular, such drugs have not been approved by the domestic health department, and domestic patients are still in the stage of “looking for plum to quench their thirst”.

traditional Chinese medicine believes that AMD belongs to the category of “dim vision”. Especially in exudative AMD, vision loss caused by neovascular membrane hemorrhage in macular area belongs to “sudden blindness”, and visual deformation caused by exudative edema in macular area belongs to “straight as curved”.

the clinical characteristics of AMD are related to the loss of essence, Qi and blood; It mainly involves kidney, spleen and liver; The syndrome types are “phlegm and blood stasis”, “blood stagnation” and “Qi Deficiency”. Exudative AMD causes recurrent macular hemorrhage due to abnormal structure of neovascular membrane. According to Jisheng Recipe on treatment of blood loss, the pathogenesis of blood loss is more due to heat. “Jing Yue Quan Shu – blood syndrome” outlines the pathogenesis of bleeding and summarizes it as “fire prosperity” and “Qi injury”. Blood syndrome theory puts forward the treatment methods of hemostasis, eliminating blood stasis, calming blood and tonifying blood. Macular edema is mostly caused by retention of water dampness and accumulation of blood stasis. “On the sources of various diseases” says that “the meridians are pungent and stagnant, and the water vapor is stagnant”, then it becomes swollen. “Blood syndrome theory” said: “blood stasis turns into water, which also becomes swelling.” Traditional Chinese medicine believes that it is the pathological products such as water, dampness and phlegm caused by obstacles in the process of water transportation and excretion, which belongs to the category of phlegm drink. It accumulates in the macula and is mostly tangible. It is treated according to phlegm and drink. Accumulation of phlegm and dampness causes detachment of retinal pigment epithelium and epithelium, and leads to retinal ischemia and hypoxia, resulting in subretinal neovascularization. Macular degeneration is mostly related to aging. For atrophic AMD, traditional Chinese medicine has long recognized that aging is closely related to “liver and kidney”. The criterion of syndrome and treatment holds that “dim vision is the disease of liver and kidney deficiency. Due to yin deficiency, less blood and semen depletion”, it provides a certain basis for the treatment of AMD from the perspective of liver and kidney. “Liver is a sea of blood” and “essence and blood alternate” reveal the mechanism of regulating hemorheological properties by tonifying liver and kidney. It is reported that taking Qiju Dihuang oral liquid or Mingmu Dihuang pill for a long time to tonify the liver and kidney changes the hemorheological parameters before and after treatment, which provides a basis for tonifying the liver and kidney in the treatment of AMD. The kidney is the foundation of congenital and the spleen is the foundation of acquired. The deficiency of essence and Qi in the elderly is closely related to the kidney and spleen. Some people take tonifying the kidney, benefiting the essence and brightening the eyes as the treatment method. Among them, Cistanche deserticola, Psoralea corylifolia and Ligustrum lucidum supplement Yin, Astragalus membranaceus replenish qi and ascend Yang, Atractylodes can dry dampness and strengthen the spleen, and Salvia miltiorrhiza and Angelica can activate blood. Dry people add Pueraria and Codonopsis pilosula to strengthen the spleen.

this formula has been proved by animal experiments that it can enhance the activity of antioxidant enzymes in eye tissue, remove free radicals, reduce the content of peroxides, delay the aging of tissues and cells, and improve microcirculation. Traditional Chinese medicine has certain advantages in the treatment of AMD. Since ancient times, traditional Chinese medicine has been treating this kind of disease according to syndrome differentiation. However, the deficiency is that only improving vision is the curative effect standard, and there is a lack of precision instruments to observe choroidal CNV lesions. Therefore, there is a lack of sufficient understanding of the occurrence and development of AMD. Traditional Chinese medicine is only in a “blind treatment stage”, with more case reports and less systematic summary. In recent 10 years, the advent of indocyanine green angiography (ICGA) and optical coherence tomography (OCT) has enabled ophthalmologists to uncover the veil of the formation of CNV in AMD. With the help of these instruments, the scope and shape of CNV can be clearly observed, which has enriched the content of the diagnosis of fundus diseases in traditional Chinese Medicine Ophthalmology, and the understanding of AMD has also taken a big step forward. The methods of

and

in traditional Chinese medicine for the treatment of this disease include decoction, patent medicine, acupuncture and moxibustion, but the theoretical source is nothing more than the treatment of deficiency, reality and both deficiency and reality. Since ancient times, there have been a variety of TCM treatment rules for AMD, regardless of one pattern. The main idea is based on syndrome differentiation and treatment. If the syndrome differentiation is appropriate, it has curative effect. However, this idea is not suitable for the observation of large samples, nor does it have the conditions for popularization and application. It is necessary to summarize a set of traditional Chinese medicine prescriptions with both theoretical guidance of traditional Chinese medicine and ophthalmic characteristics of traditional Chinese medicine, which have both curative effect and can be popularized, in order to improve the efficiency of doctors in the treatment of AMD.

warm tips: the precautions for the prevention of macular disease are to pay attention to rest at ordinary times, do not use your eyes excessively, and avoid myopia. Never turn your eyes. Pay attention to frequent and complete blinking. Frequent blinking can reduce the time of eye exposure to the air and avoid the evaporation of tears.

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. Abstract: Traditional Chinese medicine has certain advantages in the treatment of AMD. Since ancient times, traditional Chinese medicine has been treating this kind of disease according to syndrome differentiation. However, the deficiency is that it only takes improving visual acuity as the curative effect standard and lacks precise instruments to observe choroidal CNV lesions. Therefore, it lacks sufficient understanding of the occurrence and development of AMD., Macular disease is an ophthalmic disease of the elderly. If the condition is serious, it even leads to blindness. For this serious case, we must make every effort to actively treat it. How to choose the treatment method? How to choose medication? These are very concerned by patients. Let’s take a look at the specific introduction below., The advantages of traditional Chinese medicine in the treatment of age-related macular degeneration. Age-related macular degeneration is an ophthalmic refractory fundus disease, which is the primary cause of low vision and blindness in people over 50 years old. In China, the incidence rate of age-related macular degeneration is increasing year by year with the aging population. According to statistics, the incidence rate of people over 75 years old in China has reached 15.15%. At present, there are more than 1.75 million people in the United StatesThe number of people suffering from this disease is expected to reach 3 million in 10 years.,

macular disease is an ophthalmic disease of the elderly. If the condition is serious, it even leads to blindness. For this serious case, we must make every effort to actively treat it. How to choose the treatment method? How to choose medication? These are of great concern to patients. Let’s see the specific introduction below.

advantages of traditional Chinese medicine in the treatment of age-related macular degeneration

age-related macular degeneration is an ophthalmic refractory fundus disease, which is the primary cause of low vision and blindness in people over 50 years old. In China, the incidence rate of age-related macular degeneration is increasing year by year with the aging population. According to statistics, the incidence rate of people over 75 years old in China has reached 15.15%. At present, more than 1.75 million people in the United States suffer from the disease, which is expected to reach 3 million in 10 years.

in recent years, photodynamic therapy has brought some hope to the treatment of this disease, and then ushered in a new era of anti angiogenesis therapy. These two therapies are the mainstream methods of Western medicine to treat this disease. However, these two therapies still have many deficiencies. The former is expensive and easy to repeat, and it is difficult to determine whether vision can be improved. For many patients with low vision, such an expensive cost is unbearable. At present, anti vascular endothelial growth factor (anti VEGF) drugs, including ranibizumab (Lucentis), bevacizumab (Avastin) and pegaptanib (Macugen), have been used to treat neovascular AMD, namely wet AMD. Although these drugs are effective for CNV, it is difficult to control the recurrence of CNV, and there is a risk of local complications when repeated intravitreal administration is required; In particular, such drugs have not been approved by the domestic health department, and domestic patients are still in the stage of “looking for plum to quench their thirst”.

traditional Chinese medicine believes that AMD belongs to the category of “dim vision”. Especially in exudative AMD, vision loss caused by neovascular membrane hemorrhage in macular area belongs to “sudden blindness”, and visual deformation caused by exudative edema in macular area belongs to “straight as curved”.

the clinical characteristics of AMD are related to the loss of essence, Qi and blood; It mainly involves kidney, spleen and liver; The syndrome types are “phlegm and blood stasis”, “blood stagnation” and “Qi Deficiency”. Exudative AMD causes recurrent macular hemorrhage due to abnormal structure of neovascular membrane. According to Jisheng Recipe on treatment of blood loss, the pathogenesis of blood loss is more due to heat. “Jing Yue Quan Shu – blood syndrome” outlines the pathogenesis of bleeding and summarizes it as “fire prosperity” and “Qi injury”. Blood syndrome theory puts forward the treatment methods of hemostasis, eliminating blood stasis, calming blood and tonifying blood. Macular edema is mostly caused by retention of water dampness and accumulation of blood stasis. “On the sources of various diseases” says that “the meridians are pungent and stagnant, and the water vapor is stagnant”, then it becomes swollen. “Blood syndrome theory” said: “blood stasis turns into water, which also becomes swelling.” Traditional Chinese medicine believes that it is the pathological products such as water, dampness and phlegm caused by obstacles in the process of water transportation and excretion, which belongs to the category of phlegm drink. It accumulates in the macula and is mostly tangible. It is treated according to phlegm and drink. Accumulation of phlegm and dampness causes detachment of retinal pigment epithelium and epithelium, and leads to retinal ischemia and hypoxia, resulting in subretinal neovascularization. Macular degeneration is mostly related to aging. For atrophic AMD, traditional Chinese medicine has long recognized that aging is closely related to “liver and kidney”. The criterion of syndrome and treatment holds that “dim vision is the disease of liver and kidney deficiency. Due to yin deficiency, less blood and semen depletion”, it provides a certain basis for the treatment of AMD from the perspective of liver and kidney. “Liver is a sea of blood” and “essence and blood alternate” reveal the mechanism of regulating hemorheological properties by tonifying liver and kidney. It is reported that taking Qiju Dihuang oral liquid or Mingmu Dihuang pill for a long time to tonify the liver and kidney changes the hemorheological parameters before and after treatment, which provides a basis for tonifying the liver and kidney in the treatment of AMD. The kidney is the foundation of congenital and the spleen is the foundation of acquired. The deficiency of essence and Qi in the elderly is closely related to the kidney and spleen. Some people take tonifying the kidney, benefiting the essence and brightening the eyes as the treatment method. Among them, Cistanche deserticola, Psoralea corylifolia and Ligustrum lucidum supplement Yin, Astragalus membranaceus replenish qi and ascend Yang, Atractylodes can dry dampness and strengthen the spleen, and Salvia miltiorrhiza and Angelica can activate blood. Dry people add Pueraria and Codonopsis pilosula to strengthen the spleen.

this formula has been proved by animal experiments that it can enhance the activity of antioxidant enzymes in eye tissue, remove free radicals, reduce the content of peroxides, delay the aging of tissues and cells, and improve microcirculation. Traditional Chinese medicine has certain advantages in the treatment of AMD. Since ancient times, traditional Chinese medicine has been treating this kind of disease according to syndrome differentiation. However, the deficiency is that only improving vision is the curative effect standard, and there is a lack of precision instruments to observe choroidal CNV lesions. Therefore, there is a lack of sufficient understanding of the occurrence and development of AMD. Traditional Chinese medicine is only in a “blind treatment stage”, with more case reports and less systematic summary. In recent 10 years, the advent of indocyanine green angiography (ICGA) and optical coherence tomography (OCT) has enabled ophthalmologists to uncover the veil of the formation of CNV in AMD. With the help of these instruments, the scope and shape of CNV can be clearly observed, which has enriched the content of the diagnosis of fundus diseases in traditional Chinese Medicine Ophthalmology, and the understanding of AMD has also taken a big step forward. The methods of

and

in traditional Chinese medicine for the treatment of this disease include decoction, patent medicine, acupuncture and moxibustion, but the theoretical source is nothing more than the treatment of deficiency, reality and both deficiency and reality. Since ancient times, there have been a variety of TCM treatment rules for AMD, regardless of one pattern. The main idea is based on syndrome differentiation and treatment. If the syndrome differentiation is appropriate, it has curative effect. However, this idea is not suitable for the observation of large samples, nor does it have the conditions for popularization and application. It is necessary to summarize a set of traditional Chinese medicine prescriptions with both theoretical guidance of traditional Chinese medicine and ophthalmic characteristics of traditional Chinese medicine, which have both curative effect and can be popularized, in order to improve the efficiency of doctors in the treatment of AMD.

warm tips: the precautions for the prevention of macular disease are to pay attention to rest at ordinary times, do not use your eyes excessively, and avoid myopia. Never turn your eyes. Pay attention to frequent and complete blinking. Frequent blinking can reduce the time of eye exposure to the air and avoid the evaporation of tears.

. In recent years, photodynamic therapy has brought some hope to the treatment of this disease, and then ushered in a new era of anti angiogenesis therapy. These two therapies are the mainstream methods of Western medicine to treat this disease. However, these two therapies still have many deficiencies. The former is expensive and easy to repeat, and it is difficult to determine whether vision can be improved. This is true for many patients with low vision